Phenotypes Associated with This Genotype

Genotype
MGI:3807513

• Allelic Composition: Gt(ROSA)26Sor^{tm1(MAML1)Wsp}/Gt(ROSA)26Sor⁺; Pax3^tm1(cre)Joe/Pax3⁺
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal neural tube morphology ( J:130251 )

• there is a partial depletion of the progenitor zone in the neural tube of E12.5 embryos

• there is a minor decrease of under 10% in the number of dIL^B neurons found in embryos

loss of glutamate neurons ( J:130251 )

• mice exhibit a decrease in dIL^B neurons

decreased neuronal precursor cell number ( J:130251 )

• the progenitor domain is reduced compared to in wild-type mice

embryo

abnormal neural tube morphology ( J:130251 )

• there is a partial depletion of the progenitor zone in the neural tube of E12.5 embryos

• there is a minor decrease of under 10% in the number of dIL^B neurons found in embryos