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Phenotypes Associated with This Genotype
Genotype
MGI:3806713
Allelic
Composition
Rtn4rtm1Gogo/Rtn4rtm1Gogo
Genetic
Background
involves: 129 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rtn4rtm1Gogo mutation (0 available); any Rtn4r mutation (9 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• mice exhibit normal startle response, conditioned fear responses, and working memory in addition to not displaying behavioral despair
• mice do not display schizophrenia-related behaviors
• mice exhibit reduced vertical rearing in an open field test compared to wild-type mice
• mice travel reduced distances in an open field test compared to wild-type mice
• mice treated with an NMDA blocker (MK-801) exhibit decreased locomotor activity compared to similarly treated wild-type mice

Mouse Models of Human Disease
OMIM ID Ref(s)
NOT Schizophrenia; SCZD 181500 J:130368


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory