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Phenotypes Associated with This Genotype
Genotype
MGI:3806486
Allelic
Composition
Lrp5r18/Lrp5r18
Genetic
Background
C57BL/6J-Lrp5r18
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrp5r18 mutation (0 available); any Lrp5 mutation (38 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• hyperpermeable retinal vessels
• reduced density of retinal small vessels and capillaries and an attenuated and abnormally patterned vasculature due to incomplete development
• immature endothelial cells in lumen-less capillaries are associated with an attenuated vessel network

vision/eye
• hyperpermeable retinal vessels
• reduced density of retinal small vessels and capillaries and an attenuated and abnormally patterned vasculature due to incomplete development
• immature endothelial cells in lumen-less capillaries are associated with an attenuated vessel network

Mouse Models of Human Disease
OMIM ID Ref(s)
Exudative Vitreoretinopathy 4; EVR4 601813 J:135279


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory