About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3806486
Allelic
Composition
Lrp5r18/Lrp5r18
Genetic
Background
C57BL/6J-Lrp5r18
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrp5r18 mutation (0 available); any Lrp5 mutation (81 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• hyperpermeable retinal vessels
• reduced density of retinal small vessels and capillaries and an attenuated and abnormally patterned vasculature due to incomplete development
• immature endothelial cells in lumen-less capillaries are associated with an attenuated vessel network

vision/eye
• hyperpermeable retinal vessels
• reduced density of retinal small vessels and capillaries and an attenuated and abnormally patterned vasculature due to incomplete development
• immature endothelial cells in lumen-less capillaries are associated with an attenuated vessel network

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
exudative vitreoretinopathy DOID:0050535 OMIM:PS133780
J:135279


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/12/2024
MGI 6.23
The Jackson Laboratory