mortality/aging
• following infection with Listeria monocytogenes, mice exhibit increased mortality compared to similarly treated wild-type mice
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immune system
• following infection with Listeria monocytogenes, mice exhibit increased bacterial counts in the blood, spleen and lungs, increased serum cytokine levels, reduced splenocyte numbers by day 6 of infection, reduced bacterial clearance and increased mortality compared to similarly treated wild-type mice
• following infection with Staphylococcus aureus, mice exhibit increased blood and bacterial counts compared to in similarly treated wild-type mice
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