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Phenotypes Associated with This Genotype
Genotype
MGI:3805107
Allelic
Composition		 Ptcratm1Vbo/Ptcratm1Vbo
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptcratm1Vbo mutation (0 available); any Ptcra mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased DN4 thymocyte number ( J:123569 )
• mice exhibit a decrease in DN4 T cells
increased DN3 thymocyte number ( J:123569 )
• mice exhibit an increase in DN3 T cells
abnormal double-positive T cell morphology ( J:123569 )
• increase in number relative Rpl22-deficient mice

hematopoietic system
decreased DN4 thymocyte number ( J:123569 )
• mice exhibit a decrease in DN4 T cells
increased DN3 thymocyte number ( J:123569 )
• mice exhibit an increase in DN3 T cells
abnormal double-positive T cell morphology ( J:123569 )
• increase in number relative Rpl22-deficient mice

endocrine/exocrine glands
decreased DN4 thymocyte number ( J:123569 )
• mice exhibit a decrease in DN4 T cells
increased DN3 thymocyte number ( J:123569 )
• mice exhibit an increase in DN3 T cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory