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Phenotypes Associated with This Genotype
Genotype
MGI:3804667
Allelic
Composition		 Tbx6tm2Pa/Tbx6+
Wnt3atm1Amc/Wnt3a+
Genetic
Background		 involves: 129 * 129S1/Sv * 129X1/SvJ * ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tbx6tm2Pa mutation (1 available); any Tbx6 mutation (17 available)
Wnt3atm1Amc mutation (1 available); any Wnt3a mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
embryo phenotype ( J:137163 )
N
• despite decrease in Wnt3a expression in Tbx6 null mice, no defects in somite formation are detected

cardiovascular system
cardiovascular system phenotype ( J:137163 )
N
• unlike in Tbx6 null mice, the direction of heart looping is similar to controls

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory