Phenotypes Associated with This Genotype

Genotype
MGI:3803231

• Allelic Composition: Fbln1^{Gt(XST011)Byg}/Fbln1^tm1Tmpl
• Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

double outlet right ventricle ( J:137690 )

• Background Sensitivity: 11% of mice show double outlet right ventricle in conjunction with ventricular septal defects

overriding aortic valve ( J:137690 )

• Background Sensitivity: seen in about 22% of mice in conjunction with ventricular septal defects

atrial septal defect ( J:137690 )

• Background Sensitivity: 44% of hearts from mutant mice show atrial septal defects

ventricular septal defect ( J:137690 )

• Background Sensitivity: 22% of mice exhibit hearts with ventricular septal defects

• Background Sensitivity: 11% of mice show both double outlet right ventricle and ventricular septal defects

• Background Sensitivity: 22% of mice show both overriding aorta and ventricular septal defects