homeostasis/metabolism
• 40% reduction in brain 5-HT production
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behavior/neurological
• although males do not exhibit increased attacks against a non-aggressive male in a test of social interaction, they do show an increase in threatening postures
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• immobility times in the tail suspension test are prolonged
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• in the dark-light emergence test, mutants display longer latencies to cross to the lighted compartment and reduced activity in the lighted compartment
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