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Phenotypes Associated with This Genotype
Genotype
MGI:3799371
Allelic
Composition
Tg(Tcra5CC7,Tcrb5CC7)IWep/0
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Tcra5CC7,Tcrb5CC7)IWep mutation (3 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• CD4 T cells become activated when cultured with MCC peptide, HEL protein and B cells from Tg(IghelMD4)4Ccg transgenic mice
• CD4 T cell and B cell co-culturing with MCC peptide but not HEL protein induces a modest T cell activation

hematopoietic system
• CD4 T cells become activated when cultured with MCC peptide, HEL protein and B cells from Tg(IghelMD4)4Ccg transgenic mice
• CD4 T cell and B cell co-culturing with MCC peptide but not HEL protein induces a modest T cell activation


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory