Mouse Genome Informatics
hm
    Dmdmdx-5Cv/Dmdmdx-5Cv
B6Ros.Cg-Dmdmdx-5Cv/J
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
cardiovascular system
N
• despite defects in conduction, mice do not exhibit cardiac fibrosis or cellular hypertrophy in cardiac tissues (J:124861)
• heart rate and ventricular repolarization, reflected on the mouse ECG by the ST interval, are similar to controls (J:124861)
• decreased amplitude and prolonged duration (J:124861)
(J:124861)
• prolonged (J:124861)
• sodium current is decreased compared to in wild-type cardiomyocytes (J:124861)

muscle
• compared with wild-type mice (J:164891)
• mice exhibit reduced muscle contractile function compared with wild-type mice (J:164891)

Mouse Models of Human Disease
OMIM IDRef(s)
Muscular Dystrophy, Duchenne Type; DMD 310200 J:124861