Mouse Genome Informatics
hm
    Dmdmdx-5Cv/Dmdmdx-5Cv
B6Ros.Cg-Dmdmdx-5Cv/J
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
N
• despite defects in conduction, mice do not exhibit cardiac fibrosis or cellular hypertrophy in cardiac tissues
• heart rate and ventricular repolarization, reflected on the mouse ECG by the ST interval, are similar to controls
• decreased amplitude and prolonged duration
• sodium current is decreased compared to in wild-type cardiomyocytes

muscle
• compared with wild-type mice
• mice exhibit reduced muscle contractile function compared with wild-type mice

Mouse Models of Human Disease
OMIM IDRef(s)
Muscular Dystrophy, Duchenne Type; DMD 310200 J:124861