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Phenotypes Associated with This Genotype
Genotype
MGI:3798606
Allelic
Composition
Dmdmdx-3Cv/Y
Genetic
Background
involves: C3H/HeHa * C57BL/6Ros * C57BL/10Sn * M. m. castaneus * M. m musculus
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dmdmdx-3Cv mutation (2 available); any Dmd mutation (156 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
muscle
• mice exhibit skeletal muscle fiber degeneration
• electromyograms reveal peudomyotonia unlike in wild-type mice

cardiovascular system
• unlike wild-type, some cardiac fibrosis is observed

vision/eye
• although the a-wave amplitude is normal, the b-wave is attenuated by more than 50%


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory