Phenotypes Associated with This Genotype

Genotype
MGI:3789307

• Allelic Composition: En1^tm2Alj/En1^tm2Alj
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Swiss Webster

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

decreased rhombomere 1 size ( J:134516 )

• amount of rhombomere 1 tissue is reduced in mutants

decreased midbrain size ( J:134516 )

• amount of tissue is reduced in mutants

absent inferior colliculus ( J:134516 )

• structure does not form

decreased superior colliculus size ( J:134516 )

• reduced in size; in some animals only small amount of tissue forms

abnormal cerebellum morphology ( J:134516 )

• some lateral tissue is present at E18.5

abnormal cerebellum posterior vermis morphology ( J:134516 )

embryo

decreased rhombomere 1 size ( J:134516 )

• amount of rhombomere 1 tissue is reduced in mutants