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Phenotypes Associated with This Genotype
Genotype
MGI:3785509
Allelic
Composition		 Igh-Jtm1Dhu/Igh-Jtm1Dhu
Wdr1rede/Wdr1rede
Genetic
Background		 involves: 129S7/SvEvBrd * BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Igh-Jtm1Dhu mutation (1 available); any Igh-J mutation (13 available)
Wdr1rede mutation (0 available); any Wdr1 mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal immune system physiology ( J:134092 )
• the phenotype is similar to mice that are homozygote only for the Wdr1rede allele indicating that the inflammatory lesions are not the result of B-cells activity

hematopoietic system
thrombocytopenia ( J:134092 )
• three week old mice have about 5-fold less platelets per liter of blood compared to wild-type littermates

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory