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Phenotypes Associated with This Genotype
Genotype
MGI:3783816
Allelic
Composition
Slc4a7Gt(RRL021)Byg/Slc4a7Gt(RRL021)Byg
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc4a7Gt(RRL021)Byg mutation (1 available); any Slc4a7 mutation (6 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• a marked reduction in the amiloride-insensitive Na+ dependent HCO3- transport in bladder smooth muscle cells
• reduced steady-state pHi in the presence of CO2/HCo3- in resting smooth muscle cells


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory