About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3783784
Allelic
Composition
Apoa1tm1Unc/Apoa1tm1Unc
Genetic
Background
involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apoa1tm1Unc mutation (2 available); any Apoa1 mutation (16 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• HDL cholesteryl ether clearance is over 20-fold higher than in wild-type mice and varies depending on the organ examined
• however, the clearance rate could be rescued by increasing plasma HDL cholesteryl ester levels

cellular
• HDL cholesteryl ether clearance is over 20-fold higher than in wild-type mice and varies depending on the organ examined
• however, the clearance rate could be rescued by increasing plasma HDL cholesteryl ester levels


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory