Mouse Genome Informatics
hm
    Nlgn4lGt(XST093)Byg/Nlgn4lGt(XST093)Byg
B6.129P2-Nlgn4xGt(XST093)Byg
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
behavior/neurological
• attack latencies and frequency to an unfamiliar intruder mouse in the resident were reduced
• mutant mice spent 45% less time in direct contact with each other than wild-type control in an open arena
• no social preference to investigate unfamiliar mouse
• the latency to start calling and frequency of calls by male mice upon contact with a female mouse in estrous were reduced

nervous system
• small but significant reductions in the volume of the total brain and brainstem

Mouse Models of Human Disease
OMIM IDRef(s)
Autism 209850 J:131843