Mouse Genome Informatics
hm
    Pnpe/Pnpe
C57BL/6J-Pnpe
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
immune system
• marked and progressive decline in cellularity observable by 8 months of age
• spleen leukocyte response to conA and IL-2 is somewhat impaired, being 60-69% of normal

hematopoietic system
• marked and progressive decline in cellularity observable by 8 months of age
• spleen leukocyte response to conA and IL-2 is somewhat impaired, being 60-69% of normal

Mouse Models of Human Disease
OMIM IDRef(s)
Purine Nucleoside Phosphorylase Deficiency 613179 J:39328