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Phenotypes Associated with This Genotype
Genotype
MGI:3778828
Allelic
Composition
Baxtm1Sjk/Baxtm1Sjk
Nanos2tm1Ysa/Nanos2tm1Ysa
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Baxtm1Sjk mutation (1 available); any Bax mutation (24 available)
Nanos2tm1Ysa mutation (0 available); any Nanos2 mutation (15 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• male gonocytes become feminized
• male germ cells begin to disappear after birth and are gone by 4 weeks of age
• however, male germ cells do not undergo abnormal apoptosis

cellular
• male germ cells begin to disappear after birth and are gone by 4 weeks of age
• however, male germ cells do not undergo abnormal apoptosis


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory