Mouse Genome Informatics
hm
    Vangl1Gt(XL802)Byg/Vangl1Gt(XL802)Byg
involves: 129P2/OlaHsd * C57BL/6J
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       

Abnormal orientation of hair cells of the cochlea in Vangl1Gt(XL802)Byg/Vangl1Gt(XL802)Byg embryos

hearing/vestibular/ear
• modest but significant misorientation in all hair cell layers
• however, the number and organization of hair cell rows is not different from wild-type controls

cardiovascular system
N
• unlike mice homozygous for Vangl2Lp alone, nor outflow tract abnormalities are detected (J:132697)

nervous system
N
• unlike mice with mutations in Vangl2, no neural tube defects are detected (J:132697)
• modest but significant misorientation in all hair cell layers
• however, the number and organization of hair cell rows is not different from wild-type controls

Mouse Models of Human Disease
OMIM IDRef(s)
NOT Neural Tube Defects 182940 J:132697