Mouse Genome Informatics
hm
    Urostm3Rjde/Urostm3Rjde
involves: 129S6/SvEvTac * C57BL/6
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
homeostasis/metabolism
• mice have marked accumulation in bones, and display fluorescent erythrodontia
• hepatic, splenic and erythrocytic uroporphyrinogen III synthase (URO-synthase) activity is greatly reduced compared to wild-type

hematopoietic system
N
• 16-18-month old animals show similar ertythrocyte counts, hematocrits, hemoglobin concentrations, mean corpuscular volumes, and total leukocyte counts to wild-type mice (J:132542)

Mouse Models of Human Disease
OMIM IDRef(s)
Porphyria, Congenital Erythropoietic 263700 J:132542