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Phenotypes Associated with This Genotype
Genotype
MGI:3777351
Allelic
Composition
Tnfsf13btm1Msc/Tnfsf13btm1Msc
Traf2tm1Rbr/Traf2tm1Rbr
Genetic
Background
involves: 129S2/SvPas * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tnfsf13btm1Msc mutation (1 available); any Tnfsf13b mutation (28 available)
Traf2tm1Rbr mutation (0 available); any Traf2 mutation (25 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• mature B cells are virtually absent from the lymph nodes
• follicular B cells are absent from the spleen
• marginal zone B cells are absent from the spleen

hematopoietic system
• mature B cells are virtually absent from the lymph nodes
• follicular B cells are absent from the spleen
• marginal zone B cells are absent from the spleen


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory