About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3776498
Allelic
Composition
Pkd1tm1Bdgz/Pkd1+
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pkd1tm1Bdgz mutation (0 available); any Pkd1 mutation (65 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
renal/urinary system
• histologically, 30% of animals show cyst formation or tubular dilation; animals with tubular dilation are <24 weeks of age
• when gross morphology is assessed, surface cysts are observed in 19% of mutants, the majority of which are older than 24 weeks; rare animals display cyst development at 6 weeks of age
• histologically, 30% of animals show cyst formation or tubular dilation between 6 and 78 weeks of age

liver/biliary system
• when gross morphology is assessed, surface cysts are observed in 9% of mutants older than 40 weeks (seen in only 1 animal at 42 weeks)

endocrine/exocrine glands
• when gross morphology is assessed, surface cysts are observed in 1% of mutants older than 40 weeks

Mouse Models of Human Disease
OMIM ID Ref(s)
Polycystic Kidney Disease 1; PKD1 173900 J:130086


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/12/2016
MGI 6.04
The Jackson Laboratory