Phenotypes Associated with This Genotype

Genotype
MGI:3776433

• Allelic Composition: Jag2^tm1Grid/Jag2^tm1Grid
• Genetic Background: involves: 129S1/Sv * 129S1/SvImJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:132241 )

• mice do not survive postnatally

hearing/vestibular/ear

increased cochlear inner hair cell number ( J:132241 )

increased cochlear outer hair cell number ( J:132241 )

abnormal orientation of cochlear hair cell stereociliary bundles ( J:132241 )

• hair cell stereocilia bundles exhibit some disorganization

nervous system

increased cochlear inner hair cell number ( J:132241 )

increased cochlear outer hair cell number ( J:132241 )

abnormal orientation of cochlear hair cell stereociliary bundles ( J:132241 )

• hair cell stereocilia bundles exhibit some disorganization