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Phenotypes Associated with This Genotype
Genotype
MGI:3769780
Allelic
Composition
Del(7Herc2-Mkrn3)13FRdni/+
Genetic
Background
involves: C57BL/6 * CD-1 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(7Herc2-Mkrn3)13FRdni mutation (1 available); any Del(7Herc2-Mkrn3)13FRdni mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• when this allele is inherited paternally, mice die within a week of birth (J:56614)
• however, when this allele is inherited maternally mice are normal (J:56614)
• when this allele is inherited paternally, mice die within a week of birth (J:56614)
• however, when this allele is inherited maternally mice are normal (J:56614)

homeostasis/metabolism
• when this allele is inherited paternally, mice exhibit dehydration despite milk in their stomachs (J:56614)
• when this allele is inherited paternally, mice exhibit dehydration despite milk in their stomachs (J:56614)

behavior/neurological
• when this allele is inherited paternally, mice exhibit reduced movement compared to wild-type mice (J:56614)
• when this allele is inherited paternally, mice exhibit reduced movement compared to wild-type mice (J:56614)

respiratory system
• when this allele is inherited paternally, mice exhibit irregular breathing (J:56614)
• when this allele is inherited paternally, mice exhibit irregular breathing (J:56614)

cellular

Mouse Models of Human Disease
OMIM ID Ref(s)
Prader-Willi Syndrome; PWS 176270 J:56614


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory