Mouse Genome Informatics
tg
    Tg(Igh-Lmp2a)13FRdni/0
involves: C57BL/6 * CD-1 * SJL
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• when this allele is inherited paternally, mice die within a week of birth
• however, when this allele is inherited maternally mice are normal

homeostasis/metabolism
• when this allele is inherited paternally, mice exhibit dehydration despite milk in their stomachs

behavior/neurological
• when this allele is inherited paternally, mice exhibit reduced movement compared to wild-type mice

respiratory system
• when this allele is inherited paternally, mice exhibit irregular breathing

cellular

Mouse Models of Human Disease
OMIM IDRef(s)
Prader-Willi Syndrome; PWS 176270 J:56614