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Phenotypes Associated with This Genotype
Genotype
MGI:3769398
Allelic
Composition		 Ets2tm3Rgo/Ets2tm3Rgo
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ets2tm3Rgo mutation (1 available); any Ets2 mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
abnormal trophoblast layer morphology ( J:128952 )
• when transfected with an adenovirus Cre, trophoblast stem cells exhibit reduced growth and self-renewal
• however, trophoblast cells transfected with an adenovirus Cre differentiate normally

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory