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Phenotypes Associated with This Genotype
Genotype
MGI:3764493
Allelic
Composition
Camk2atm4Sva/Camk2atm4Sva
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Camk2atm4Sva mutation (0 available); any Camk2a mutation (63 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
N
• unlike in Camk2atm2Sva homozygotes, field excitatory postsynaptic potential and synaptic plasticity are normal
• long term potentiation is increased upon weak stimulation (150 theta bursts at 50 Hz)
• however, long term potentiation is normal upon strong stimulation (4 theta bursts at 100 Hz)


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory