Phenotypes Associated with This Genotype

Genotype
MGI:3764008

• Allelic Composition: Myb^tm1.1Cgn/Myb⁺
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

arrested B cell differentiation ( J:127234 )

• block at pro- to pre-B cell transition is seen in young mice

decreased mature B cell number ( J:127234 )

• reduced in spleen at younger ages

decreased B-1 B cell number ( J:127234 )

• numbers are decreased in spleen and peritoneal cavity at 10-16 weeks of age

decreased pre-B cell number ( J:127234 )

• numbers are reduced in bone marrow and persists over time

immune system

arrested B cell differentiation ( J:127234 )

• block at pro- to pre-B cell transition is seen in young mice

decreased mature B cell number ( J:127234 )

• reduced in spleen at younger ages

decreased B-1 B cell number ( J:127234 )

• numbers are decreased in spleen and peritoneal cavity at 10-16 weeks of age

decreased pre-B cell number ( J:127234 )

• numbers are reduced in bone marrow and persists over time