Phenotypes Associated with This Genotype

Genotype
MGI:3762494

• Allelic Composition: Lime1^tm1.1Mal/Lime1^tm1.1Mal; Rag2^tm1Fwa/Rag2^tm1Fwa; Tg(TcraH-Y,TcrbH-Y)1Pas/?
• Genetic Background: B6.Cg-Rag2^tm1Fwa Lime1^tm1.1Mal Tg(TcraH-Y,TcrbH-Y)1Pas

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

abnormal CD4-positive T cell differentiation ( J:126321 )

• 1.8 fold increase in clonotype positive cells in the thymus of female but not male mice

increased CD4-positive, alpha-beta T cell number ( J:126321 )

• 3 fold increase in clonotype CD4 T cells in female but not male mice

immune system

abnormal CD4-positive T cell differentiation ( J:126321 )

• 1.8 fold increase in clonotype positive cells in the thymus of female but not male mice

increased CD4-positive, alpha-beta T cell number ( J:126321 )

• 3 fold increase in clonotype CD4 T cells in female but not male mice