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Phenotypes Associated with This Genotype
Genotype
MGI:3761174
Allelic
Composition
Tg(MMTV-neu/OT-I/OT-II)CBnel/?
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(MMTV-neu/OT-I/OT-II)CBnel mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
tumorigenesis
• only ~50% of females develop mammary tumors by 16 months of age (J:122846)
• only ~50% of females develop mammary tumors by 16 months of age (J:122846)
• ~37% of mammary tumor-bearing mice frequently have lung metastases consisting of >1mm tumor cell emboli growing within blood vessels (J:122846)
• ~37% of mammary tumor-bearing mice frequently have lung metastases consisting of >1mm tumor cell emboli growing within blood vessels (J:122846)

Mouse Models of Human Disease
OMIM ID Ref(s)
Breast Cancer 114480 J:122846


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory