About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3761174
Allelic
Composition
Tg(MMTV-neu/OT-I/OT-II)CBnel/?
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(MMTV-neu/OT-I/OT-II)CBnel mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
respiratory system
• ~37% of mammary tumor-bearing mice frequently have lung metastases consisting of >1mm tumor cell emboli growing within blood vessels

endocrine/exocrine glands
• only ~50% of females develop mammary tumors by 16 months of age

integument
• only ~50% of females develop mammary tumors by 16 months of age

neoplasm
• only ~50% of females develop mammary tumors by 16 months of age
• ~37% of mammary tumor-bearing mice frequently have lung metastases consisting of >1mm tumor cell emboli growing within blood vessels

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
breast cancer DOID:1612 OMIM:114480
OMIM:600048
OMIM:605365
J:122846


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/14/2017
MGI 6.11
The Jackson Laboratory