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Phenotypes Associated with This Genotype
Genotype
MGI:3722163
Allelic
Composition		 Tg(PRNP-APPSweInd)8Dwst/0
Genetic
Background		 involves: 129S6/SvEvTac * C3H/HeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:69967 )
• Background Sensitivity: survival decreases to 25-40% within 120 days of life; only 17% (7/41) survive to 365 days

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory