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Phenotypes Associated with This Genotype
Genotype
MGI:3720088
Allelic
Composition
Hbab3(th)/Hba+
Genetic
Background
SEC-Hbab3(th)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hbab3(th) mutation (0 available); any Hba mutation (12 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• many pups die between birth and weaning

hematopoietic system
• at E13.5 - E15.5, eosinophilic inclusions are seen in liver derived erythrocytes
• however, no abnormalities are seen in yolk-sac derived nucleated erythrocytes

growth/size/body
• newborn pups are smaller than wild-type littermates
• reduced in heterozygous adults to 18.77 +/- 0.59g compared to 23.79 +/- 0.39g in wild-type mice

Mouse Models of Human Disease
OMIM ID Ref(s)
Alpha-Thalassemia 604131 J:6452


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory