Phenotypes Associated with This Genotype

Genotype
MGI:3719989

• Allelic Composition: Xist^tm2.1Jae/Xist⁺
• Genetic Background: involves: 129

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

abnormal dosage compensation, by inactivation of X chromosome ( J:95871 )

♀ • E7.0 embryos exhibit selective inactivation of the wild-type allele instead of the random inactivation observed in wild-type embryos

embryo

embryonic growth retardation ( J:174672 )

♀ • when the allele is inherited paternally, female mice exhibit severe developmental defect at E7.5 compared with control mice

growth/size/body

embryonic growth retardation ( J:174672 )

♀ • when the allele is inherited paternally, female mice exhibit severe developmental defect at E7.5 compared with control mice