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Phenotypes Associated with This Genotype
Genotype
MGI:3718233
Allelic
Composition
Hoxa11tm1Ssp/Hoxa11tm1Ssp
Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu
Genetic
Background
involves: 129S2/SvPas * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxa11tm1Ssp mutation (0 available); any Hoxa11 mutation (11 available)
Hoxd11tm2.1Ddu mutation (0 available); any Hoxd11 mutation (14 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
skeleton
• 2 of 2 mice have carpal bone defects
• pisiform and pyramidal bones are fused and attached to the navicular-lunate
• radius and ulna are abnormally broad
• radius and ulna are abnormally broad
• 2 of 2 mice have abnormal L4
• 2 of 2 mice have an L7 formula instead of an L6 formula found in wild-type mice

limbs/digits/tail
• 2 of 2 mice have carpal bone defects
• pisiform and pyramidal bones are fused and attached to the navicular-lunate
• radius and ulna are abnormally broad
• radius and ulna are abnormally broad


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory