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Phenotypes Associated with This Genotype
Genotype
MGI:3716303
Allelic
Composition
Zic1tm1Jaru/Zic1+
Genetic
Background
B6.129S4-Zic1tm1Jaru
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zic1tm1Jaru mutation (2 available); any Zic1 mutation (17 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mutants exhibit reduced horizontal motor activity

muscle
• mutants perform worse in a wire-hanging test than wild-type, however maximal grip strength is normal, indicating that muscle tone, but not maximal muscle strength, is reduced
• mutants show a slight, but significant reduction in ability to remain on a stationary rod, however show no difference in the retention time on a rotating rod

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
Joubert syndrome DOID:0050777 OMIM:PS213300
J:72342


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory