Phenotypes for Epb41l5 MGI:3715174 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Epb41l5^{Gt(AE0088)Wtsi}/Epb41l5^lulu
Genetic Background	involves: C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Epb41l5^{Gt(AE0088)Wtsi} mutation (0 available); any Epb41l5 mutation (46 available)
Epb41l5^lulu mutation (0 available); any Epb41l5 mutation (46 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality between somite formation and embryo turning ( J:122548 )

• embryos recapitulate Epb4.1l5^lulu phenotype

embryo

abnormal rostral-caudal body axis extension ( J:122548 )

• at E8.5, embryos have shortened trunks

abnormal neural plate morphology ( J:122548 )

• at E8.5, anterior neural plate is broad, open, and folded into irregular ridges, and thicker than in wild-type

absent somites ( J:122548 )

• embryos lack visible somites at E8.5

nervous system

abnormal neural plate morphology ( J:122548 )

• at E8.5, anterior neural plate is broad, open, and folded into irregular ridges, and thicker than in wild-type

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23