Phenotypes Associated with This Genotype

Genotype
MGI:3714987

• Allelic Composition: Tbx18^tm1Akis/Tbx18^tm1Akis
• Genetic Background: involves: 129S1/SvImJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal vein morphology ( J:122633 )

• at E14.5, veins within the heart are thinner and smaller and are abnormally positioned within the membranous wall

• at the cranial level, veins are shifted laterally and are surrounded by lung tissue

• myocardial differentiation of the walls of the systemic veins is delayed

abnormal common cardinal vein morphology ( J:122633 )

• at E10.5, all mice fail to form a left sinus horn in the pericadial cavity

• at E10.5, sinus horn precursor cells are decreased

abnormal heart morphology ( J:122633 )

• at E14.5, hearts have thinner and smaller veins that are abnormally positioned within the membranous wall