Mouse Genome Informatics
ot
    Dp(16Lipi-Zfp295)1Yey/0
involves: 129S7/SvEvBrd
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• only 38% of mice are alive at weaning

cardiovascular system
• seen in 1 of 30 embryos at E18.5
• at E18.5, about 37% of mice have heart defects including cleft of the mitral valve, atrial septal defect, perimembranous ventricular septum defect, conal ventricular septum defect, overriding of the aorta, narrowed outflow tract of the right ventricle, tetralogy of Fallot, double outlet right ventricle and coarcation of the aorta
• seen in one of 30 embryos at E18.5
• seen in 2 of 30 embryos at E18.5
• clefting seen in 3 of 30 embryos at E18.5
• seen in 4 of 30 embryos at E18.5
• seen in 5 of 30 embryos at E18.5
• seen in 2 of 30 embryos at E18.5
• seen in 2 of 30 embryos at E18.5

digestive/alimentary system
• at E18.5, 33% of mice have malrotation of the intestine

endocrine/exocrine glands
• at E18.5, in about 26% of mice

Mouse Models of Human Disease
OMIM IDRef(s)
Pancreas, Annular 167750 J:121790
Tetralogy of Fallot; TOF 187500 J:121790