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Phenotypes Associated with This Genotype
involves: 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dp(16Lipi-Zbtb21)1Yey mutation (3 available); any Dp(16Lipi-Zbtb21)1Yey mutation (3 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
• only 38% of mice are alive at weaning

cardiovascular system
• seen in 1 of 30 embryos at E18.5
• at E18.5, about 37% of mice have heart defects including cleft of the mitral valve, atrial septal defect, perimembranous ventricular septum defect, conal ventricular septum defect, overriding of the aorta, narrowed outflow tract of the right ventricle, tetralogy of Fallot, double outlet right ventricle and coarcation of the aorta
• seen in one of 30 embryos at E18.5
• seen in 2 of 30 embryos at E18.5
• clefting seen in 3 of 30 embryos at E18.5
• seen in 4 of 30 embryos at E18.5
• seen in 5 of 30 embryos at E18.5
• seen in 2 of 30 embryos at E18.5
• seen in 2 of 30 embryos at E18.5

digestive/alimentary system
• at E18.5, 33% of mice have malrotation of the intestine

endocrine/exocrine glands
• at E18.5, in about 26% of mice

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
annular pancreas DOID:0060850 OMIM:167750
tetralogy of Fallot DOID:6419 OMIM:187500

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory