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Phenotypes Associated with This Genotype
Genotype
MGI:3712469
Allelic
Composition
Thbdtm2Emc/Thbdtm2Emc
Genetic
Background
either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• during hypoxia 7 of 18 mice die with diffuse lung fibrin depositions compared to only one wild-type mouse

immune system
• leukocyte accumulation in the lung is increased

hematopoietic system
• leukocyte accumulation in the lung is increased

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
thrombophilia DOID:2452 OMIM:188050
OMIM:614486
J:118000


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory