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Phenotypes Associated with This Genotype
Genotype
MGI:3712286
Allelic
Composition
Mecp2tm2Bird/Mecp2+
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mecp2tm2Bird mutation (1 available); any Mecp2 mutation (27 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• at 4 to 12 months of age, mice exhibit a progressive development of RTT-like symptoms (inertia, gait, hindlimb clasping, tremor, irregular breathing and poor general condition)
• at 4 to 12 months of age
• at 4 to 12 months of age

growth/size/body
• mice exhibit excess weight gain

nervous system
• mice develop a reduction in long term potentiation

respiratory system
• at 4 to 12 months of age

Mouse Models of Human Disease
OMIM ID Ref(s)
Rett Syndrome; RTT 312750 J:118365


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory