Mouse Genome Informatics
ht
    Mecp2tm2Bird/Mecp2+
involves: 129P2/OlaHsd * C57BL/6
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• at 4 to 12 months of age, mice exhibit a progressive development of RTT-like symptoms (inertia, gait, hindlimb clasping, tremor, irregular breathing and poor general condition)
• at 4 to 12 months of age
• at 4 to 12 months of age

growth/size/body
• mice exhibit excess weight gain

nervous system
• mice develop a reduction in long term potentiation

respiratory system
• at 4 to 12 months of age

Mouse Models of Human Disease
OMIM IDRef(s)
Rett Syndrome; RTT 312750 J:118365