Mouse Genome Informatics
ht
    Mecp2tm2Bird/Mecp2+
involves: 129P2/OlaHsd * C57BL/6
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
behavior/neurological
• at 4 to 12 months of age, mice exhibit a progressive development of RTT-like symptoms (inertia, gait, hindlimb clasping, tremor, irregular breathing and poor general condition) (J:118365)
• at 4 to 12 months of age (J:118365)
• at 4 to 12 months of age (J:118365)

growth/size
• mice exhibit excess weight gain (J:118365)

nervous system
• mice develop a reduction in long term potentiation (J:118365)

respiratory system
• at 4 to 12 months of age (J:118365)

Mouse Models of Human Disease
OMIM IDRef(s)
Rett Syndrome; RTT 312750 J:118365