Mouse Genome Informatics
ht
    Elovl4tm1Wked/Elovl4+
involves: 129S/SvEv * 129S1/Sv
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
vision/eye
• at 9 months of age there is an abnormal accumulation of the lipofuscin component N-retinylidene-N-retinylethanolamine (A2E) precursors (87% more A2PE-H and 31% more A2PE) (J:121481)
• at 8 months of age, mice a reduced rod amplitude (100+/-19 compared to 164+/-33 in wild-type) (J:121481)
• reduced vision (J:121481)

pigmentation
• at 9 months of age there is an abnormal accumulation of the lipofuscin component N-retinylidene-N-retinylethanolamine (A2E) precursors (87% more A2PE-H and 31% more A2PE) (J:121481)

Mouse Models of Human Disease
OMIM IDRef(s)
Stargardt Disease 3; STGD3 600110 J:121481