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Phenotypes Associated with This Genotype
Genotype
MGI:3706952
Allelic
Composition		 Ts(1217)4Rk/0
Genetic
Background		 involves: AEJ/GnRk * C3H/He * C57BL/6J * DBA/2J
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See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal male germ cell morphology ( J:117029 )
• significantly more sperm with head abnormalities
oligozoospermia ( J:117029 )
• sperm concentration was significantly reduced below controls
decreased sperm progressive motility ( J:117029 )
• significantly reduced frequencies of sperm with progressive motility
decreased testis weight ( J:117029 )
• significantly smaller testes than controls
arrest of male meiosis ( J:117029 )
• spermatogenesis was arrested at meiosis (prophase or metaphase I) in many tubules
male infertility ( J:117029 )
• produced no progeny
• fail to produce a vaginal plug

cellular
abnormal male germ cell morphology ( J:117029 )
• significantly more sperm with head abnormalities
oligozoospermia ( J:117029 )
• sperm concentration was significantly reduced below controls
decreased sperm progressive motility ( J:117029 )
• significantly reduced frequencies of sperm with progressive motility

endocrine/exocrine glands
decreased testis weight ( J:117029 )
• significantly smaller testes than controls

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory