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Phenotypes Associated with This Genotype
Genotype
MGI:3702933
Allelic
Composition		 Slc6a3tm1(cre)Lrsn/Slc6a3+
Sncatm1Nbm/Sncatm1Nbm
Tfamtm1Lrsn/Tfamtm1Lrsn
Genetic
Background		 involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc6a3tm1(cre)Lrsn mutation (1 available); any Slc6a3 mutation (66 available)
Sncatm1Nbm mutation (5 available); any Snca mutation (42 available)
Tfamtm1Lrsn mutation (1 available); any Tfam mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
neuronal intranuclear inclusions ( J:119515 )
• triple mutants show same phenotype as Tfamtm1Lrsn, Slc6a3tm1(cre)Lrsn mice; neuronal inclusions remain indicating that additional lack of Snca is not required for develoment of the Parkonsonian phenotype

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory