Mouse Genome Informatics
cx
    Spry2tm1Ayos/Spry2tm1Ayos
Spry4tm1Ayos/Spry4tm1Ayos

involves: 129 * C57BL/6J
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging

vision/eye

craniofacial
• craniofacial abnormalities

limbs/digits/tail
• limb abnormalities

nervous system
• severe truncation of the forebrain and cephalic neural crest-derived head tissues
• alobar brain development and cyclopia resemble holoprosencephaly

respiratory system
• exhibit abnormalities of the lung pattern and epithelial branching

Mouse Models of Human Disease
OMIM IDRef(s)
Apert Syndrome 101200 J:116506