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Phenotypes Associated with This Genotype
Genotype
MGI:3699097
Allelic
Composition
Htttm1.1Tna/Htt+
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Htttm1.1Tna mutation (0 available); any Htt mutation (25 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• exhibit an increase in glial fibrillary acidic protein (GFAP)-positive cells in the substantia nigra and the globus pallidus at 40 weeks of age, indicating astrocytosis (J:76017)
• exhibit an increase in glial fibrillary acidic protein (GFAP)-positive cells in the substantia nigra and the globus pallidus at 40 weeks of age, indicating astrocytosis (J:76017)

Mouse Models of Human Disease
OMIM ID Ref(s)
Huntington Disease; HD 143100 J:76017


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory