Phenotypes for Mapkapk2 MGI:3698631 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Mapkapk2^tm1Mgl/Mapkapk2^tm1Mgl
Genetic Background	involves: 129P2/OlaHsd * 129S/SvEvBrd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mapkapk2^tm1Mgl mutation (0 available); any Mapkapk2 mutation (36 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

abnormal cytokine secretion ( J:117668 )

• LPS-induced production of tristetraprolin and TNF is reduced compared to wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23