Phenotypes Associated with This Genotype

Genotype
MGI:3697485

• Allelic Composition: Atp1a3^tm1Ling/Atp1a3⁺
• Genetic Background: involves: 129 * Black Swiss

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

enhanced behavioral response to addictive substance ( J:117414 )

• increase in peak activity elicited by methamphetamine

abnormal spatial learning ( J:117414 )

• increased latency to find the platform in a Morris water maze

hyperactivity ( J:117414 )

• significant increase in activity in the first 4 time intervals in an open field

• increase in peak activity elicited by methamphetamine

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:117414 )

N • circulating levels of corticosterone, norepinephrine, dopamine, serotonin, and their metabolites are all similar to wild-type mice