Mouse Genome Informatics
hm
    Krt4Bcc1/Krt4Bcc1
C3HeB/FeJ-Krt4Bcc1
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• slight but significant reduction in survival

craniofacial
• mild lymphocytic infiltration in the submucosa
• primarily on the tongue but also found on the palatal and esophageal mucosa
• mucosal thickening and cytolysis of the spinous layer within lesions; however, the basal cell layer is intact
• normal architecture is absent and the tissue is friable

digestive/alimentary system
• mild lymphocytic infiltration in the submucosa
• primarily on the tongue but also found on the palatal and esophageal mucosa
• mucosal thickening and cytolysis of the spinous layer within lesions; however, the basal cell layer is intact
• normal architecture is absent and the tissue is friable

growth/size/body
• mild lymphocytic infiltration in the submucosa
• primarily on the tongue but also found on the palatal and esophageal mucosa
• mucosal thickening and cytolysis of the spinous layer within lesions; however, the basal cell layer is intact
• normal architecture is absent and the tissue is friable
• runted and underdeveloped by 2 weeks of age

Mouse Models of Human Disease
OMIM IDRef(s)
White Sponge Nevus 1; WSN1 193900 J:116740