About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3695719
Allelic
Composition
Krt4Bcc1/Krt4Bcc1
Genetic
Background
C3HeB/FeJ-Krt4Bcc1
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• slight but significant reduction in survival (J:116740)
• slight but significant reduction in survival (J:116740)

craniofacial
• mild lymphocytic infiltration in the submucosa (J:116740)
• mild lymphocytic infiltration in the submucosa (J:116740)
• primarily on the tongue but also found on the palatal and esophageal mucosa (J:116740)
• mucosal thickening and cytolysis of the spinous layer within lesions; however, the basal cell layer is intact (J:116740)
• primarily on the tongue but also found on the palatal and esophageal mucosa (J:116740)
• mucosal thickening and cytolysis of the spinous layer within lesions; however, the basal cell layer is intact (J:116740)
• normal architecture is absent and the tissue is friable (J:116740)
• normal architecture is absent and the tissue is friable (J:116740)

digestive/alimentary system
• mild lymphocytic infiltration in the submucosa (J:116740)
• mild lymphocytic infiltration in the submucosa (J:116740)
• primarily on the tongue but also found on the palatal and esophageal mucosa (J:116740)
• mucosal thickening and cytolysis of the spinous layer within lesions; however, the basal cell layer is intact (J:116740)
• primarily on the tongue but also found on the palatal and esophageal mucosa (J:116740)
• mucosal thickening and cytolysis of the spinous layer within lesions; however, the basal cell layer is intact (J:116740)
• normal architecture is absent and the tissue is friable (J:116740)
• normal architecture is absent and the tissue is friable (J:116740)

growth/size/body
• mild lymphocytic infiltration in the submucosa (J:116740)
• mild lymphocytic infiltration in the submucosa (J:116740)
• primarily on the tongue but also found on the palatal and esophageal mucosa (J:116740)
• mucosal thickening and cytolysis of the spinous layer within lesions; however, the basal cell layer is intact (J:116740)
• primarily on the tongue but also found on the palatal and esophageal mucosa (J:116740)
• mucosal thickening and cytolysis of the spinous layer within lesions; however, the basal cell layer is intact (J:116740)
• normal architecture is absent and the tissue is friable (J:116740)
• normal architecture is absent and the tissue is friable (J:116740)
• runted and underdeveloped by 2 weeks of age (J:116740)
• runted and underdeveloped by 2 weeks of age (J:116740)

Mouse Models of Human Disease
OMIM ID Ref(s)
White Sponge Nevus 1; WSN1 193900 J:116740


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/02/2016
MGI 6.02
The Jackson Laboratory