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Phenotypes Associated with This Genotype
Genotype
MGI:3693882
Allelic
Composition
Flt1tm1Gne/Flt1tm1Gne
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Flt1tm1Gne mutation (0 available); any Flt1 mutation (73 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• corneal inection of plasmids encoding cre recombinase to delete Flt1 in the cornea induces corneal vascularization, but has no effect in wild-type mice; topical application of cell-permeable cre to the cornea to avoid trauma also induces vascularization in mutants but not wild-type

cardiovascular system
• corneal inection of plasmids encoding cre recombinase to delete Flt1 in the cornea induces corneal vascularization, but has no effect in wild-type mice; topical application of cell-permeable cre to the cornea to avoid trauma also induces vascularization in mutants but not wild-type


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory