About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3689381
Allelic
Composition
Cftrtm3Mrc/Cftrtm3Mrc
Genetic
Background
B6.129S6-Cftrtm3Mrc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cftrtm3Mrc mutation (0 available); any Cftr mutation (31 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
respiratory system
• abnormal nasal potential difference
• increased inflammatory response to chronic Pseudomonas aeruginosa infection, identical to that in Cftrtm1Unc homozygotes

growth/size/body
• reduced at 14 and 21 days of age relative to wild-type mice

digestive/alimentary system
• develop intestinal blockage when fed a normal (solid) diet

immune system
• increased inflammatory response to chronic Pseudomonas aeruginosa infection, identical to that in Cftrtm1Unc homozygotes

Mouse Models of Human Disease
OMIM ID Ref(s)
Cystic Fibrosis; CF 219700 J:112450


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/19/2016
MGI 6.03
The Jackson Laboratory