Mouse Genome Informatics
hm
    Cftrtm3Mrc/Cftrtm3Mrc
B6.129S6-Cftrtm3Mrc
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
respiratory system
• abnormal nasal potential difference
• increased inflammatory response to chronic Pseudomonas aeruginosa infection, identical to that in Cftrtm1Unc homozygotes

growth/size
• reduced at 14 and 21 days of age relative to wild-type mice

digestive/alimentary system
• develop intestinal blockage when fed a normal (solid) diet

immune system
• increased inflammatory response to chronic Pseudomonas aeruginosa infection, identical to that in Cftrtm1Unc homozygotes

Mouse Models of Human Disease
OMIM IDRef(s)
Cystic Fibrosis; CF 219700 J:112450